Is Your Brain Older Than You Are? The New Science of ‘Brain Age’

Researchers can now estimate a brain’s age from structural MRI data — and it often differs from chronological age. A 2025 study of more than 41,000 participants found the gap predicts Alzheimer’s risk, mortality, and a range of lifestyle factors. Here is what the evidence shows, and where it honestly stops.

Why Chronic Pain Can Become a Brain-Wide Experience

A 2026 meta-analysis of 48 whole-brain fMRI studies and 2,052 participants examined what the brain does during pain in people with chronic primary pain — and found a pattern that extends well beyond the expected pain circuits.

What If ‘Brain Fog’ Isn’t One Thing at All?

People recovering from COVID, going through perimenopause, managing poor sleep, and recovering from concussion all describe remarkably similar cognitive symptoms. The experience converges. The biology doesn’t.